The Hyperglycemia-induced Inflammatory Response in Adipocytes

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The Hyperglycemia-induced Inflammatory Response in Adipocytes

From the Departments of ‡Cell Biology, ¶Pathology, and **Medicine, and the §§Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York 10461, the §Departments of Medicine and Physiology and Banting and Best Diabetes Center, University of Toronto, Toronto, Ontario M5G 1X5, Canada, the ABR-Affinity BioReagents, Golden, Colorado 80403, and the ‡‡Pacific Northwest ...

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The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.

Hyperglycemia is a major independent risk factor for diabetic macrovascular disease. The consequences of exposure of endothelial cells to hyperglycemia are well established. However, little is known about how adipocytes respond to both acute as well as chronic exposure to physiological levels of hyperglycemia. Here, we analyze adipocytes exposed to hyperglycemia both in vitro as well as in vivo...

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Anti-Inflammatory Effects of Atorvastatin by the Modulation of NF-κB Expression during Hyperglycemia-Induced Nephropathy in Rat

Objective: Atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. Therefore, this study considered to examine the effects of atorvastatin on NF-қB expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. Materials and Methods: Twenty four male Wistar rats were randomly divided into four g...

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The Effect of Creatine Monohydrate Loading on Downhill Running-induced Inflammatory Response in Elite Male Mountaineers

Abstract Background & Aims: In regard to the limited studies about the effect of creatine on exercise-induced inflammatory responses, the present study was conducted to identify the effect of creatine monohydrate loading on response of serum C-reactive protein (CRP), interleukin-6 (IL-6) and peripheral blood leucocytes following one bout downhill running in male mountain climbers. Methods: Twen...

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Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced inflammatory response

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2005

ISSN: 0021-9258

DOI: 10.1074/jbc.m411863200